Our collaborative and multidisciplinary translational tumor immunology group (https://pirl.unc.edu/) is seeking to hire a research associate who is highly skilled in cytometry and functional analysis of T cells to lead a project discovering tumor antigen-specific T cell receptors and mechanisms of resistance to antigen-specific T cell cytotoxicity in NUT carcinoma. The goal of this research is to develop novel immunotherapies for this cancer which has a poor prognosis and very few if any good therapeutic options. The successful applicant will be able to conceive, plan, and execute experiments independently, as well as to analyze data and lead a small team in executing research goals in collaboration with principal investigators and other lab members. Beyond cytometry and functional T cell studies, experimental work will include single cell transcriptomic and T cell receptor analyses using human cell lines, primary tumor samples, and murine models. There will be substantial interaction with lab members working in bioinformatics and computational biology as well as opportunity for training in these areas if the applicant desires. As part of this work, they will be expected to lead and contribute to academic products including presentations, manuscripts, and patents deriving from their experimental results. If desired, the applicant will have the opportunity to be the lead author on presentations, manuscripts, and grants derived from their work.
Minimum Education and Experience Requirements
Relevant post-Baccalaureate degree required (or foreign degree equivalent); for candidates demonstrating comparable independent research productivity, will accept a relevant Bachelor\'s degree (or foreign degree equivalent) and 3 or more years of relevant experience in substitution. May require terminal degree and licensure.
Required Qualifications, Competencies, and Experience
The successful applicant should have at minimum a Bachelor\'s degree in immunology (or similar discipline) with relevant experience and documented expertise in leading research projects through to completion. They will also have demonstrated technical excellence in cytometry (flow cytometry and/or mass cytometry) including processing of samples for high-quality cytometry analysis.
Preferred Qualifications, Competencies, and Experience
Preferred qualifications include (1) PhD in immunology, (2) experience with processing samples from both human and murine peripheral blood and tumor tissues, (3) experience with genomics studies and bioinformatics tools to analyze data from these, (4) experience with team leadership and project management in research collaborations.
Special Physical/Mental Requirements
Campus Security Authority Responsibilities
Not Applicable.
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Posting Contact Information
Department Contact Name and Title Vanessa Perry HR Consultant
Department Contact Telephone or Email vanessa_perry@med.unc.edu
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