Job Description

job summary:
BioMedicine Design group (BMD) is seeking a creative and self-motivated Senior Associate Scientist to join their team. The candidate will play an essential role in a high-energy RNA and biotherapeutic platform development research laboratory. The candidate will participate in development and innovation of RNA-based therapeutics at a pre-clinical stage. They will be responsible for in-vitro transcription optimization (IVT), purification, and cell-based characterization of new RNA designs using a broad range of molecular biology-based technologies and equipment. The candidate will also contribute to the group wide deliverables.

location: Cambridge, Massachusetts
job type: Contract
salary: $35.00 - 39.44 per hour
work hours: 9 to 5
education: Bachelors

responsibilities:
- Perform efficient IVT & purification protocols for novel RNA therapeutic candidates.

- Perform and support development of molecular biology assays to assess RNA quality and quantification

- Perform functional assessment of RNA in cell culture models

- Routinely provide updates at project meetings and maintain updated records

- Drive technology innovation: design and implement molecular biology strategies to enable small scale analysis of RNAs

- Work closely with multidisciplinary teams including therapeutic discovery teams and R&D project leaders

qualifications:
Must-Have

- BS with 2-4 years or MS with 0-2 years of relevant experience in Molecular Biology, Biochemistry, Biology, Biomedical Sciences, or a related discipline

- Knowledgeable in nucleic acid biology, and IVT or RNA stability

- Hands-on experience with general molecular biology methods, specifically RNA isolation and assessment techniques such as qPCR, ddPCR, TapeStation or Fragment Analyzer

- Hands-on experience with aseptic cell culture techniques using mammalian cells

- Knowledgeable in preparative and analytical chromatography methods

- Strong written and oral communication skills and ability to work effectively in cross functional teams

- Organized, detail oriented, multi-task, and remain flexible with changing needs

- Must be self-motivated, curious and able to work under strict timeline with limited supervision once trained

Nice-To-Have

- Prior experience in cellular assays (including plate based assay, gel analysis, FACS, etc).

- Prior experience with purification (using affinity and traditional chromatographic techniques) on AKTA chromatography systems

- Experience in therapeutic drug discovery, gene therapy or RNA therapeutics

- Nucleic acid based molecular biology methods

- Mammalian cell culture and cell-based assays

- Self-motivated and scientifically curious, able to work collaboratively, with strong communication skills

Hard Skills:

- Hands-on experience with general molecular biology methods, specifically RNA isolation and assessment techniques such as qPCR, ddPCR, TapeStation or Fragment Analyzer

Not protein, Must have Knowledgeable in nucleic acid biology, and IVT or RNA stability.

Mammalian Cells, not bacterial

Soft Skills:

- Team Environment, cross functional with other teams.

skills: Molecular Biology, Biology, Cell Cultures

Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.

At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact HRsupport@randstadusa.com.

Pay offered to a successful candidate will be based on several factors including the candidate\'s education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including health, an incentive and recognition program, and 401K contribution (all benefits are based on eligibility).

Randstad