Job Description

Working with Us
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Position: Scientific Executive Director

Location: Cambridge, MA

Position Summary

The Neuroscience TRC is committed to development of transformational therapeutics for patients with neurodegenerative and neuromuscular diseases. We have built a network of external partnerships across multiple treatment modalities (small molecules, biologics and RNA targeting) that leverage our leadership in protein homeostasis and inflammation to attack neurological diseases. Internal research focuses on protein homeostasis by direct and ligand directed degradation, neuroinflammation and remyelination and novel approaches to neurodegeneration target and drug discovery.

Areas of interest include, but are not limited to, the following approaches:

Disease modifying therapies for neurodegenerative, neuro-inflammatory, and neuromuscular diseases; CNS targets that modulate protein homeostasis, protein clearance, inflammation and reduce or eliminate toxic protein production; Emerging technologies (RNA, DNA targeting, gene regulation, editing and gene therapy) that when matched to underlying disease genetics can deliver a precision medicine portfolio with a high probability of success to address unmet medical needs. We are interested in common neurodegenerative diseases and opportunistic applications in orphan/rare neurological and neuromuscular diseases. Our group is actively engaged in the use of AI/ML to augment our discovery and translational approaches and are developing novel tools for clinical trials including digital neuroimaging and fluid biomarkers to track neurodegenerative disease.

We seek a talented senior scientist to combine expert knowledge in neurodegeneration and drug discovery to contribute to our departmental leadership, evolution, and portfolio.

The candidate will help drive our early discovery portfolio of innovative internal programs and external strategic alliances that aims to combine cutting edge drug discovery approaches with a growing understanding of the genetics of neurodegeneration. The candidate will have the opportunity to develop strategies for discovery within the NS TRC and across BMS expertise in high throughput biology, chemistry, and computational sciences. The candidate will participate and lead the development and management of an array of external collaborations with projects ranging from early target discovery to IND submission.

As part of the Discovery Biology Group within the Neuroscience Thematic Research Center (NS TRC) the successful candidate will develop applications for target and drug discovery that utilize a variety of approaches including human inducible pluripotent stem cell derived neurons and glial cells and help progress projects from target validation to clinical development.

The successful candidate will be an important leader of NS Discovery Biology group, located in Cambridge MA. The NS TRC is a highly collaborative department, working across our locations with many colleagues throughout the Research & Early Development (R/ED) organization. The position offers an exciting opportunity to make a difference in lives of patients, gain industry experience, and interact with the broader scientific community. The successful candidate will also be encouraged to publish their work and to present at external meetings and conferences.

Key Responsibilities

In the role as Executive Director within the Neuroscience TRC, the ideal candidate:

Applies leading-edge knowledge of principles, concepts, practices, and techniques to lead highly complex projects involving multi-disciplinary groups and external organizations

Is recognized as an influential authority across the company and in the external community and is a known subject matter expert that provides strategic and functional guidance in neurodegeneration and drug discovery and development

Recognizes and champions programs and initiatives to support strategic research goals and direction across multiple disciplines

Recommends expansion or curtailment of investigations on the basis of experimental results or scientific information

Delivers results that have an impact on company performance strategically, financially, and operationally

Is a proven leader whose expertise is sought after by the external community

Acts as a role model for a culture of responsible risk-taking and curiosity

Is involved in initiatives that encourage and develop this capability in others and is an active mentor for developing scientific leadership and excellence at all levels

Identifies, initiates, and leads strategic collaborations within and outside the company to drive long-term value to the business

Maintains a high level of contribution to the discipline through publishing / presentations / patents

Provides effective coaching and feedback to help develop team members and colleagues within and outside of department

Develop programs to systematically validate novel targets and progress drug discovery efforts in neurodegeneration

Develop opportunities to combine cutting edge technologies, BMS expertise and neuroscience expertise to develop new programs in neurodegeneration

Participate and help lead external collaborations with academic and biotechnology groups to help progress our target and drug discovery efforts

Identify and champion opportunities for collaboration across BMS expertise

Develop programs to systematically validate novel targets and progress drug discovery efforts in neurodegeneration

Develop opportunities to combine cutting edge technologies, BMS expertise and neuroscience expertise to develop new programs in neurodegeneration

Participate and help lead external collaborations with academic and biotechnology groups to help progress our target and drug discovery efforts

Identify and champion opportunities for collaboration across BMS expertise

Qualifications & Experience

Basic Qualifications:

Master\'s Degree

20+ years of academic / industry experience

Or

PhD

15+ years of academic / industry experience

10+ years of leadership experience

Preferred Qualifications: Demonstrated experience and success in neuroscience drug discovery, application of a variety of approaches in target validation, high throughput biology and drug discovery

Broad knowledge in neurodegeneration and ability to rapidly learn expertise and contribute to new areas of research

Experience leading a diverse set of scientific programs and cross functional teams

Experience and ability to lead directly within an organization and across internal and external indirect relationships

Excellent communication skills, enthusiasm work in a highly matrixed team environment and vigorous open scientific exchange are essential

Excellent interpersonal, management and mentorship skills and comfort and experience managing across diverse expertise and cultures

Strong ability to challenge the status quo as well as a drive to make others successful

If you come across a role that intrigues you but doesn\xe2\x80\x99t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as \xe2\x80\x9cTransforming patients\xe2\x80\x99 lives through science\xe2\x84\xa2 \xe2\x80\x9d, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Bristol-Myers Squibb