Job Description

Proteomics Bench Scientist

Andover, MA

|

Contract (12 months)

|

Schedule:

Monday - Friday, 1st Shift (Flexible)

Position Summary

We are seeking a highly skilled

Proteomics Bench Scientist

to join our bioanalytical research team. The ideal candidate will bring expertise in

LC-MS-based proteomics

and play a key role in developing and optimizing workflows using advanced

high-resolution mass spectrometry

. This role involves hands-on method development, sample preparation from complex biological matrices, and advanced bioinformatics-driven data analysis.

This position is best suited for scientists who thrive in a collaborative, fast-paced laboratory environment and are eager to apply their proteomics expertise toward innovative drug discovery and development efforts.

Key Responsibilities

Develop, optimize, and implement

proteomics workflows

for sample preparation and mass spectrometry analysis. Apply advanced

quantitative proteomics techniques

(TMT, DIA, label-free) for in-depth protein profiling. Operate and maintain

high-resolution mass spectrometry instruments

(Orbitraps, timsTOF). Perform

bioinformatics-driven data analysis

, including database searching, statistical modeling, and data visualization. Collaborate with cross-functional scientists to design experiments and advance research objectives. Maintain accurate, detailed records in an

Electronic Lab Notebook (ELN)

. Participate in regular project meetings, contributing expertise and scientific insights.

Qualifications

Education & Experience:

PhD

in a relevant scientific discipline (preferred), or

M.Sc. + 5+ years

of documented experience in proteomics and mass spectrometry.

Required Technical Skills:

Expertise in

mass-spectrometry-based proteomics

(TMT, DIA, label-free quantification). Proven experience with

high-resolution MS instruments

(Orbitraps, timsTOF). Strong background in

protein sample preparation

, including affinity purification and universal protein extraction. Proficiency with

bioinformatics tools

for proteomics data processing, statistics, and visualization.

Preferred Skills:

Experience with

membrane protein or cell surface proteomics

. Hands-on knowledge of

cell culture techniques

and

cell-based assays

. Familiarity with handling

biohazardous or NHP (non-human primate) samples

.

Work Environment & Requirements

Onsite role, laboratory-based with daily interaction across cross-functional teams. Physical requirements include standing, sitting, walking, and stair use as appropriate for lab work. Interviews will be conducted in two rounds:

Round 1:

Microsoft Teams (virtual)

Round 2:

Onsite interview
Job Type: Contract

Pay: $48.00 - $55.00 per hour

Expected hours: 40 per week

Benefits:

Dental insurance Health insurance Vision insurance
Work Location: In person