Job Description

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together.
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Scientific Director Oncology - ETCT Innovation
The Extracellular Targeted Cancer Therapeutics (ETCT) Biology Unit within the Oncology Research Unit is seeking a Scientific Director for Innovation to lead outwardly facing technology and business development initiatives designed to accelerate the build of a targeted biologics portfolio in Oncology. The incumbent will lead cross-functional initiatives to develop the next generation of ADC and interface with key internal/external business partners to accelerate asset development. Additionally, this position will involve consultation with the business development team to assist the identification and assessment of cutting-edge technologies and potential research collaborations. The successful applicant will have prior experience leading matrix teams with oversight of critical path chemistry and biology in the preclinical development of ADC for cancer therapy.
Please note: This position requires an on-site office -based presence 2 to 3 days a week in the UK (Stevenage); Switzerland (Zug); US (Upper Providence, PA. Waltham. MA); or Poland (Warsaw).
Responsibilities:
As a Scientific Director for Innovation in ETCT, your responsibilities will be to:

• Guide the maturation and de-risking of novel therapeutic concepts, specifically antibody drug conjugates (ADCs), through rigorous mechanistic testing in partnership with internal and external business partners.
• Talent scout new technology investments and help build proposals for GSK's senior leadership for investment.
• Co-lead a team which can collaborate with internal platform groups to deliver success on externally partnered programs and/or technologies.
• Identify new areas for investment at the preclinical research phase, as well as assist scientific due diligence review of in-licensing clinical opportunities with the business development organization.
• Prioritize innovation projects and allocate resources effectively to drive successful outcomes.
• Collaborate with business development teams to establish strategic partnerships and alliances with external organizations, including startups, research institutions, and pharmaceutical companies.

Why You?
Basic Qualifications:
We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

• PhD in Cancer Biology, Pharmacology, Cellular Biology, or related life science fields with 5+ years post-doctoral training.
• Experience leading cross-functional drug discovery project teams oversighting critical path chemistry and biology to develop novel therapeutic platforms for biologics targets.
• Direct experience developing ADC, and novel chemistry.
• Experience developing and implementing scientific strategies in Oncology or related disciplines with 12 to 24-month planning horizons.
• Experience in progressing ADC from concept to candidate selection and supporting critical path mechanistic biology and/or in vivo translational studies.

Preferred Qualifications
If you have the following characteristics, it would be a plus:

• 10+ years pharmaceutical or biotechnology industry research and leadership experience in preclinical oncology biologics drug discovery.
• Experience establishing scientific relationships in Oncology.
• Experience working with business development to perform due diligence on oncology assets
• Strong peer-reviewed publication, public speaking / presentation and/or inventorship record.
• The ability to work independently with excellent organizational and interpersonal skills.

We encourage you to apply if you are excited about the opportunity to make a difference and grow your career in a supportive and innovative environment.
Please visit to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
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